Atypical chronic lymphocytic leukemia with polyglandular autoimmune endocrinopathy type II: a complex profile

Polyglandular autoimmune syndrome type II.

The polyglandular autoimmune syndromes (PAS) comprise a wide spectrum of autoimmune disorders. There exist a juvenile (PAS I) and an adult type (PAS II). The nature of PAS has been based on the presence of lymphocyte infiltration in the affected gland, organ-specific antibodies in the serum, cellular immune defects and an association with the human leucocyte antigen (HLA) DR/DQ genes or immune ...

Autoimmune polyglandular syndrome, type II.

The combination of autoimmune adrenal insufficiency with autoimmune thyroid disease and/or type 1 autoimmune diabetes mellitus defines autoimmune polyglandular syndrome, type II. The conditions may occur in any order, and diagnosis is confounded by the nonspecific nature of the symptoms of adrenal insufficiency and hypothyroidism. The disorder is not common, but consequences can be life threate...

Autoimmune thrombocytopenic purpura ("ITP" type) with chronic lymphocytic leukemia.

Achalasia in a Patient with Polyglandular Autoimmune Syndrome Type II

Achalasia is a rare disease characterized by aperistalsis of the esophageal body and failure of the lower esophageal sphincter to relax. The etiology of this disease remains unknown. Polyglandular autoimmune syndrome type II is a well-identified disease characterized by the occurrence of autoimmune Addison's disease in combination with autoimmune thyroid disease and/or type 1 diabetes mellitus....

[Chronic autoimmune urticaria as a possible non endocrine manifestation of autoimmune polyglandular syndrome type II].

The autoimmune polyglandular syndromes are infrequent Alpha-trypsin and complement factors C3 and C4, as well as factor B, were normal. Serological testing for HBV, HCV and HIV proved negative. With the suspicion of autoimmune chronic urticaria (ACU), autologous serum testing was carried out and proved positive, thereby confirming the disease. Following the failure of other treatments with oral...